Targets of functional imaging

Metabolism
Perfusion (blood flow)
Neurotransmitter systems
Steroid hormones
Infection and inflammation
Biologics and biosimilars
Protein deposits (proteinopathies)
Organs and tissues


Literature

Alam IS, Arshad MA, Nguyen Q, Aboagye EO. Radiopharmaceuticals as probes to characterize tumour tissue. Eur J Nucl Med Mol Imaging 2015; 42: 537-561. doi: 10.1007/s00259-014-2984-3.

Cumming P, Vasdev N. The assay of enzyme activity by positron emission tomography. Neuromethods 2012; 71: 111-135. doi: 10.1007/7657_2012_53.

Holland JP, Cumming P, Vasdev N. PET radiopharmaceuticals for probing enzymes in the brain. Am J Nucl Med Mol Imaging 2013; 3(3): 194-216. PMID: 23638333.

Neumann K, Flavell R, Wilson DM. Exploring metabolism in vivo using endogenous 11C metabolic tracers. Semin Nucl Med. 2017; 47: 461-473. doi: 10.1053/j.semnuclmed.2017.05.003.

Sosuke Miyoshi, Keisuke Mitsuoka, Shintaro Nishimura and Stephan A. Veltkamp (2011). Radioisotopes in Drug Research and Development: Focus on Positron Emission Tomography, Radioisotopes - Applications in Bio-Medical Science, Prof. Nirmal Singh (Ed.), ISBN: 978-953-307-748-2, InTech, doi: 10.5772/22728.

Vāvere AL, Scott PJH. Clinical applications of small-molecule PET radiotracers: current progress and future outlook. Semin Nucl Med. 2017; 47: 429-453. doi: 10.1053/j.semnuclmed.2017.05.001.

Wong DF, Gründer G, Brasic JR. Brain imaging research: Does the science serve clinical practice? Int Rev Psychiatry 2007; 19(5): 541-558. PMID: 17896234.



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Updated at: 2023-01-23
Created at: 2007-10-22
Written by: Vesa Oikonen