fr4sim 3.9.2 © 1998-2012 by Turku PET Centre
Simulation programs calculate tissue curve values with short sample
time intervals. This program sums up those points within specified time
frames to simulate a measured PET tissue uptake curve.
Usage:
fr4sim [Options] <datafile> <frames data> <output datafile> [isotope]
Options:
-i Calculates integrals at frame mid times, instead of averages;
not available with [isotope].
-ii Calculates 2nd integrals at frame mid times, instead of averages;
not available with [isotope].
-sec or -min
Sample times are known to be in seconds or minutes, but is not
specified or is wrong in DFT files.
-mid
Frame mid time is written in output file instead of start and end times
-h or --help
Print this message and exit
-v, --version, or --build
Print software build information and exit
--silent
Program works silently, printing only error and warning messages
--verbose
Program prints more information about what it is doing.
Input datafile can contain one or more data columns in any DFT format (1).
Frames data can be in SIF format (2). Alternatively, frames data file can
consist of one or two columns of data, containing either
1) frame durations or 2) frame start times and frame durations;
time units must be same as in the datafile. Frames are allowed to overlap.
If the isotope is specified, the correction for physical decay is at first
removed, then PET framing is simulated, and after that the framed data
is decay corrected again, based on the frame start time and length as is
the normal procedure when collecting PET image data.
Check that time units are correct when using this possibility.
Output is written in DFT format (1) depending on the format of the input.
References:
1. TAC file:
http://www.turkupetcentre.net/analysis/doc/format_dft.html
2. SIF file:
http://www.turkupetcentre.net/analysis/doc/sif.html
See also:
tacframe,
tactime,
dftdecay,
tacunit,
interpol,
extrapol,
dftint
Keywords: DFT, simulation, time frame, SIF, interpolation
This program comes with ABSOLUTELY NO WARRANTY. This is free software, and
you are welcome to redistribute it under GNU General Public License.
