extrapol - tpcclib 0.8.0 © 2023 by Turku PET Centre
Extrapolation of the decreasing tail of PET input curve to given time.
This is accomplished by fitting line to the end-part of the plot of the
natural logarithm of tracer concentration against time.
This approach may be applied to TACs which approach zero; thus this
works best for metabolite-corrected input TACs, and cannot be used with
tracers with very slow clearance, such as radiowater.
Usage: extrapol [Options] inputfile time outputfile
Options:
-e[nd]=<Fit end time>
Start the search to fit end time; by default, the search for the best
line fit is started from the last sample.
-minnr=<Minimum nr of samples>
Set the minimum number of samples used in searching the best fit;
by default 3.
-maxnr=<Maximum nr of samples>
Set the maximum number of samples used in searching the best fit;
by default all samples.
-mintime=<Minimum time>
Set a minimum time range used in searching the best fit.
-svg=<Filename>
Measured and extrapolated TACs are plotted in specified SVG file.
-h, --help
Display usage information on standard output and exit.
-v, --version
Display version and compile information on standard output and exit.
-d[n], --debug[=n], --verbose[=n]
Set the level (n) of debugging messages and listings.
-q, --quiet
Suppress displaying normal results on standard output.
-s, --silent
Suppress displaying anything except errors.
Input TAC file must contain a time column, and one or more concentration
columns. The extrapolation time must be given in same units as are the sample
times in the datafile.
See also: paucinf, avgbolus, fit_dexp, fit_feng, fit2dat, tacln
Keywords: input, plasma, TAC, modelling, simulation