yokoi - tpcclib 0.8.0 © 2023 by Turku PET Centre
Calculate K1, k2, and K1/k2 using multiple-time graphical analysis (MTGA)
for reversible PET ligands (Yokoi plot) (1,2,3) from regional PET TACs.
Usage: yokoi [options] tacfile input starttime endtime resultfile
Options:
-sd=<y|N>
Standard deviations are saved (y) or not saved (n, default) in results.
-svg=<Filename>
Plots are written in specified file in Scalable Vector Graphics (SVG) 1.1
format; specification in http://www.w3.org/TR/SVG/
-plot=<Filename>
Data for plots is written in TSV format for easy importing in Excel
or OpenOffice spreadsheet, where the data can be viewed.
-h, --help
Display usage information on standard output and exit.
-v, --version
Display version and compile information on standard output and exit.
-d[n], --debug[=n], --verbose[=n]
Set the level (n) of debugging messages and listings.
-q, --quiet
Suppress displaying normal results on standard output.
-s, --silent
Suppress displaying anything except errors.
References:
1. Yokoi T, Iida H, Itoh H, Kanno I. A new graphic plot analysis for cerebral
blood flow and partition coefficient with iodine-123-iodoamphetamine
and dynamic SPECT validation studies using oxygen-15-water and PET.
J Nucl Med. 1993; 34(3): 498-505.
2. Ito H, Yokoi T, Ikoma Y, et al. A new graphic plot analysis for
determination of neuroreceptor binding in positron emission tomography
studies. NeuroImage 2010; 49(1): 578-586.
3. Ito H, Ikoma Y, Seki C, et al. Visual evaluation of kinetic
characteristics of PET probe for neuroreceptors using a two-phase graphic
plot analysis. Ann Nucl Med. 2017; 31(4): 273-282.
See also: logan, patlak, fitk2, lhsol
Keywords: TAC, MTGA, modelling, K1, Vt