imgfur - tpcclib 0.8.0 © 2023 by Turku PET Centre
Calculates of Fractional Uptake Rate (FUR) or FUR-based Metabolic Rate (MR)
image from static or dynamic PET image in ECAT 6.3 or 7.2, NIfTI, or
Analyze 7.5 format. Information on FUR in:
http://www.turkupetcentre.net/petanalysis/model_fur.html
Usage: imgfur [Options] inputfile image starttime endtime furimage
FUR calculation start and stop time must be entered in minutes;
set both to zero to use the whole time range from image data.
Options:
-Ca=<value>
Concentration of native substrate in arterial plasma (mM),
for example plasma glucose in [18F]FDG studies.
With this option the metabolic rate (umol/(min*100 g)) is calculated.
-LC=<value>
Lumped Constant in MR calculation; default is 1.0.
-density=<value>
Tissue density in MR calculation; default is 1.0 g/ml.
-h, --help
Display usage information on standard output and exit.
-v, --version
Display version and compile information on standard output and exit.
-d[n], --debug[=n], --verbose[=n]
Set the level (n) of debugging messages and listings.
-q, --quiet
Suppress displaying normal results on standard output.
-s, --silent
Suppress displaying anything except errors.
Example 1. Calculation of FUR image from a dynamic image from 45 to 60 min:
imgfur ua2918ap.kbq ua2918dy1.v 45 60 ua2918fur.v
Example 2. Calculation of glucose uptake image, when tissue density is 1.04,
plasma glucose concentration is 5.2 mM, lumped constant is 0.52, from
a static (one frame) image:
imgfur -density=1.04 -Ca=5.2 -LC=0.52 a864ap.kbq a864dy1.v 0 0 a864mrglu.v
The unit of pixel values in the FUR image is
(mL plasma)/(min*(mL tissue)) by default, and umol/(min*100 g) in metabolic
rate image.
See also: imgki, imginteg, imgcalc, ecattime, img2tif, regfur
Keywords: image, modelling, FUR, retention index, irreversible uptake